mantispy.tl.percent_replicating

mantispy.tl.percent_replicating(adata, groupby='Metadata_Perturbation', metric='pearson', use_rep=None, null_size=10000, quantile=0.95, seed=0, key_added='percent_replicating', copy=False)

Median replicate correlation against a non-replicate null.

An older readout, largely replaced by mAP. It thresholds rather than ranks, and it depends on the number of replicates per perturbation. It is included because many published results report it.

Return type:

AnnData | None

Returns:

None, or the modified copy. Writes a per-group table to uns["mantispy"][key_added] and a summary dict to uns["mantispy"][key_added + "_summary"].